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CHE 546: Molecular Spectroscopy and Structure (variable credits)	offered yearly
For the nonspecialist. Three topics each semester, chosen from the list below. Prereq for all topics; CHE 356 or equivalent. Students may register for one, two, or three modules. • 546M Atomic Spectroscopy and Angular Momentum, 1 credit • 546M Laser Chemistry and Spectroscopy, 1 credit • 546M Symmetry and Group Theory, 1 credit • 546M Electronic Spectroscopy, 1 credit • 546M Nuclear Magnetic Resonance Spectroscopy, 1 credit • 546M Vibrational Spectroscopy, 1 credit • 546M Laser Applications of Molecular Spectroscopy, 1 credit   » Syllabus (Spring '09)

CHE 575: Organic Spectroscopy (3 cr)	offered yearly
Use of mass spectroscopy and infrared, ultraviolet-visible, and nuclear magnetic resonance spectroscopy. Prereq: CHE 325 and 326 or permission of instructor.

CHE 600: Selected Topics in Chemistry (1-3 cr)   » Syllabus (Fall '09, Inorganic Chemistry of Main Group Elements)	offered irregularly

CHE 611/411: Inorganic Chemistry (3 cr)	offered yearly
Descriptive and structural inorganic chemistry and underlying principles. Prereq: CHE 346 or 375.   » Syllabus (Fall '09)

CHE 612/412: Metals in Medicine (3 cr)	offered yearly
Bonding, stereochemistry, and properties of metallo-drugs and diagnostic agents. Topics include platinum compounds for treating cancer, gadolinium and technetium in biomedical imaging, and porphyrins in photo-dynamic therapy. Laboratory experiments emphasize the main topics covered in lecture. Additional work required of graduate students. Prereq: CHE 356, 474 or permission of instructor.   » Syllabus (abbreviated) (Spring '10)

CHE 615: Main Group Chemistry (3 cr)	offered every other year
The s- and p-block elements and their compounds, chemical properties, reactivity, structure, function, and applications. Organometallic, coordination chemistry and solid state aspects of main group inorganic chemistry employing physical methods to investigate observed trends.

CHE 616: Solid State Chemistry (3 cr)	offered every other year
The description and understanding of extended chemical structures, phase diagrams, and the interplay of chemical-bonding-structure. Symmetry and other factors governing the structures and physical properties of solid state materials.

CHE 622/422: Inorganic Laboratory Techniques (1 cr)	offered yearly
Basic experimental techniques used in inorganic chemistry. Prereq. or coreq: CHE 611/411.   » Syllabus (Spring '09)

CHE 624: Advances in Inorganic Chemistry (1 cr)
Recent advances in inorganic chemistry will be presented and discussed. Individual topics for the various modules of the course will be taught by experts in the field and will vary from year to year. Repeatability 3. Modular titles are: • 624M Inorganic Chemistry of Main Group Elements • 624M Materials Chemistry/Nanoscience and Nanotechnology • 624M Biomedical Applications in Inorganic Chemistry • 624M Organometallic and Main Group Chemistry

CHE 625: Crystallography (3 cr)	offered every other year
Modern methods of structure determination using x-ray crystallography. Symmetry and space groups will be developed, as well as the mathematical foundation of practical crystallography. Model structures will be determined.

CHE 626: Organometallic Chemistry (3 cr)	offered every other year
Topics in current organometallic and organotransition metal chemistry emphasizing structure, bonding, properties, reactions, and reaction mechanisms of organometallic species including stoichiometric and catalytic reagents in asymmetric and related pathways.

CHE 627/427: Intermediate Organic Chemistry (3 cr)	offered yearly
Stereochemistry, photochemistry, natural products, and chemistry of reactive intermediate and retrosynthetic analysis and design. For Chemistry majors interested in organic specialization and graduate students wishing to strengthen fundamental concepts. Prereq: CHE 325, 326.   » Syllabus (Fall '09)

CHE 634: Advanced Chemical Instrumentation and Analytical Techniques (3 cr)	offered every other year
Fundamentals of instrumentation, spectral data analysis, chemometrics, and analytical applications in various areas of molecular spectroscopy, such as ultraviolet-visible absorption and fluorescence, electronic and vibrational circular dichroism, surface laser spectroscopy, and laser Raman scattering.

CHE 636/436: Advanced Physical Chemistry (3 cr)	offered yearly
Applications of thermodynamics and quantum mechanics to chemical bonding, molecular properties, chemical kinetics, structure of matter, spectroscopy. Prereq: CHE 356.   » Syllabus (Fall '09)

CHE 645: Quantum Mechanics in Chemistry (3 cr)	offered yearly
The fundamentals of quantum mechanics, with application to simple systems, complex atoms and molecules.

CHE 655: Quantum Chemistry and Advanced Quantum Mechanics (3 cr)	offered upon sufficient student interest
Fundamentals of quantum chemistry, molecular bonding (e.g., MO-SCF, C.I.), time-dependent phenomena, scattering, density matrices. Prereq: CHE 645.

CHE 656: Chemical Thermodynamics (3 cr)
Phenomenological approach. Chemical equilibria and solution behavior. Principles of molecular thermodynamics introduced.   » Syllabus (Spring '09)

CHE 666: Statistical Mechanics (3 cr)	offered every other year
Quantum-statistical treatment in terms of canonical and grand canonical ensembles of systems of noninteracting and interacting particles. Chemical applications of statistical thermodynamics, elementary theory of transportation processes, fluctuations, and irreversible processes.

CHE 674/474: Structural and Physical Biochemistry I (3 cr)	offered yearly
Thermodynamics, kinetics, and bonding associated with biological molecules. The course also utilizes computerbased molecular modeling tools for analyzing the structures of drugs, proteins, and nucleic acids. Additional work required of graduate students. Prereq: CHE 275, 325.   » Syllabus (Fall '09)

CHE 675: Advanced Organic Chemistry (3 cr)	offered yearly
Structure and stereochemistry, chirality, conformational analysis. Molecular orbital theories and applications to organic chemistry. Aromaticity. Introduction to organic mechanisms. Methods of deciphering organic mechanisms. Prereq: one year of elementary organic chemistry; one year of elementary physical chemistry.   » Syllabus (Fall '09) - coming soon

CHE 676: Introduction to Organic Synthesis: Methodology (3 cr)	offered yearly
Functional group transformations and carbon-carbon bond-forming reactions. Basic design strategies and advanced synthetic techniques including protection and functional group equivalency.   » Syllabus (Fall '09)

CHE/BCM 677/477: Preparation and Analysis of Proteins and Nucleic Acids (3 cr)	offered yearly
Experimental methods for biologically synthesizing and chemically purifying macromolecules in order to analyze their structure and function, including polymerase chain reaction; site-directed mutagenesis; protein expression and purification; nucleic acid and protein electrophoresis. Additional work required of graduate students. Prereq: CHE 107 or 129; CHE 474, or BIO 326. Coreq: BIO 575.   » Syllabus (Spring '09)

CHE 685: Organic Mechanisms (3 cr)	offered yearly
Ionic mechanisms: displacements, addition eliminations, arrangements. Catalysis. Free radical mechanisms. Molecular mechanisms, including applications of orbital symmetry and frontier molecular orbital theory to organic reactions. Prereq: one year of elementary and physical chemistry.   » Syllabus (Spring '09)

CHE 686: Advanced Organic Synthesis: Design (3 cr)	offered yearly
The design, planning, and execution of multi-step organic syntheses. Asymmetric, enzymatic, and solid phase synthetic methods. Retrosynthetic analysis and combinatorial techniques.   » Syllabus (Spring '09)

CHE 690: Independent Study (1-6 cr)	offered every semester

CHE 997: Master's Thesis (1-6 cr)	offered every semester

CHE 999: Doctoral Dissertation (1-15 cr)	offered every semester

Biochemistry

BCM 630/430: Journal Club in Molecular Pharmacology and Structural Biology (1 cr)
Critical evaluation of recent journal articles that focus on molecular pharmacology and/or structural biology. Students make at least one presentation per semester and participate in weekly discussion. Additional work required of graduate students. Permission of instructor.

BCM/CHE 677/477: Preparation and Analysis of Proteins and Nucleic Acids (3 cr)	offered yearly
Experimental methods for biologically synthesizing and chemically purifying macromolecules in order to analyze their structure and function, including polymerase chain reaction; site-directed mutagenesis; protein expression and purification; nucleic acid and protein electrophoresis. Additional work required of graduate students. Prereq: CHE 107 or 129; CHE 474, or BIO 326. Coreq: BIO 575.   » Syllabus (Spring '09)

BCM 684/484: Biomolecular Modeling (2-3 cr)	offered every other year
Experience in biomolecular modeling of proteins, nucleic acids, and drug candidates as practice in biochemical research and technology. Connections with structural and physical principles will be emphasized. Additional work required of graduate students. Prereq for BCM 484: CHE 474; for BCM 684: Graduate standing and permission of instructor.   » Syllabus (Spring '09)